Generic-reference and generic-generic bioequivalence of forty-two, randomly-selected, on-market generic products of fourteen immediate-release oral drugs
نویسندگان
چکیده
منابع مشابه
Bioequivalence of generic drugs.
Generic drugs are bioequivalent to the original brand; this is a prerequisite for marketing approval. It is theoretically possible that one generic drug may overestimate the pharmacokinetic (PK) parameters of the original and another generic may underestimate these PK parameters; in consequence, these 2 generics may not be bioequivalent between themselves. The result could be loss of efficacy o...
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ژورنال
عنوان ژورنال: BMC Pharmacology and Toxicology
سال: 2017
ISSN: 2050-6511
DOI: 10.1186/s40360-017-0182-1